How does Bravecto work against ticks on dogs? - briefly
Bravecto works against ticks on dogs by targeting and killing both immature and adult stages of ticks within 48 hours of attachment. The active ingredient in Bravecto, fluralaner, acts as a systemic ectoparasiticide, which means it spreads throughout the dog's body and is transferred to the tick when it feeds on the dog's blood.
How does Bravecto work against ticks on dogs? - in detail
Bravecto is an innovative ectoparasiticide that demonstrates exceptional efficacy against ticks on dogs, primarily due to its active ingredient, fluralaner. The mode of action of Bravecto involves several key mechanisms that collectively contribute to its robust tick control properties.
Firstly, fluralaner acts as a potent inhibitor of gamma-aminobutyric acid (GABA) and glutamate-gated chloride channels in the parasite's nervous system. These channels are essential for the transmission of neurotransmitters, which regulate various physiological processes in ticks. By blocking these channels, fluralaner disrupts the normal functioning of the tick's nervous system, leading to paralysis and eventual death.
Additionally, fluralaner exhibits a unique pharmacokinetic profile that enhances its effectiveness against ticks. Once administered, Bravecto is rapidly absorbed into the dog's bloodstream, where it maintains high concentrations for an extended period. This sustained release of the active ingredient ensures continuous exposure to ticks attempting to feed on the treated dog. The persistent presence of fluralaner in the bloodstream guarantees that any tick that attaches will be exposed to a lethal dose, effectively preventing infestation.
Moreover, Bravecto demonstrates a rapid speed of kill against ticks. Within 12 hours of administration, the product begins to exhibit its effects on ticks, leading to significant mortality within 24-48 hours. This swift action is crucial for controlling tick infestations and minimizing the risk of tick-borne diseases, such as Lyme disease and ehrlichiosis, which can be transmitted to dogs and even humans.
Bravecto's efficacy against ticks is further bolstered by its broad spectrum of activity. It targets a wide range of tick species, including those that are resistant to other ectoparasiticides, such as permethrin and fipronil. This comprehensive coverage ensures that dogs receiving Bravecto are protected against multiple tick threats, providing peace of mind for pet owners.
In summary, Bravecto's effectiveness against ticks on dogs is underpinned by its active ingredient fluralaner, which inhibits essential neurotransmitter channels in the parasite's nervous system. Its unique pharmacokinetic profile, rapid speed of kill, and broad spectrum of activity collectively contribute to Bravecto's exceptional tick control properties, making it a reliable choice for protecting dogs against tick infestations and associated health risks.