How much Isoniazid to give a dog?

How much Isoniazid to give a dog? - briefly

The recommended dosage of isoniazid for dogs is typically 10-15 mg/kg orally once daily. It's crucial to consult with a veterinarian before administering any medication to ensure proper dosage and safety.

How much Isoniazid to give a dog? - in detail

Isoniazid is a medication commonly used in humans to treat tuberculosis and other mycobacterial infections. However, its use in dogs requires careful consideration due to species-specific differences in metabolism and potential side effects. Here's a comprehensive overview of how much Isoniazid to give a dog:

Isoniazid is not frequently prescribed for dogs, but when it is, the dosage typically ranges from 5 to 10 milligrams per kilogram of body weight (mg/kg), administered orally once or twice daily. The exact dosage depends on the specific condition being treated and the dog's overall health status.

When prescribing Isoniazid for a dog, veterinarians must take into account several factors:

  • Body Weight: Accurately measuring the dog's weight is crucial to determine the correct dosage.
  • Condition Treated: Different conditions may require different dosages. For instance, treating leprosy in dogs might necessitate a higher dose compared to other mycobacterial infections.
  • Concurrent Medications: Isoniazid can interact with other medications, so the veterinarian must consider any concurrent treatments.
  • Liver Function: Since Isoniazid is metabolized by the liver, dogs with hepatic impairment may require a lower dosage to avoid toxicity.

It's essential to note that Isoniazid should only be administered under veterinary supervision. Overdosing can lead to serious side effects, including seizures and liver damage. Additionally, some dogs may experience adverse reactions even at therapeutic doses, such as anorexia, lethargy, and gastrointestinal upset.

In summary, while Isoniazid can be a useful medication for treating specific conditions in dogs, its use must be carefully managed by a veterinarian. The typical dosage ranges from 5 to 10 mg/kg, administered orally once or twice daily, but the exact amount depends on various factors including the dog's weight, the condition being treated, and any concurrent medications or health issues. Always consult with a veterinary professional before initiating treatment with Isoniazid in dogs.