What does an elevated SF in a blood biochemical analysis mean in a dog? - briefly
An elevated serum ferritin (SF) level in a dog’s blood biochemical analysis typically indicates increased iron storage, often associated with conditions such as inflammation, liver disease, or hemolytic disorders.
What does an elevated SF in a blood biochemical analysis mean in a dog? - in detail
An elevated Serum Ferritin (SF) level in a blood biochemical analysis of a dog indicates an increased concentration of ferritin, a protein that stores iron in the body. This elevation can be associated with various underlying conditions, including inflammation, infection, liver disease, or certain types of cancer. Ferritin is an acute-phase reactant, meaning its levels can rise in response to systemic inflammation or tissue damage. In cases of liver disease, such as hepatitis or cirrhosis, the liver’s ability to regulate iron storage may be compromised, leading to elevated SF levels. Additionally, hemolytic anemia, a condition where red blood cells are destroyed prematurely, can cause an increase in ferritin as the body attempts to store excess iron released from damaged cells. Neoplasms, particularly those involving the liver, spleen, or bone marrow, may also contribute to elevated SF due to increased cellular turnover and iron release. It is essential to interpret elevated SF in conjunction with other diagnostic findings, such as complete blood count, liver enzyme levels, and imaging studies, to determine the specific cause. Further diagnostic workup, including additional blood tests, ultrasound, or biopsy, may be necessary to identify the underlying condition and guide appropriate treatment. Monitoring SF levels over time can also help assess the progression of the disease and the effectiveness of therapeutic interventions.