What is VOV in dogs? - briefly
VOV (Vertebral Osteochondrosis) in dogs refers to a developmental disorder affecting the vertebrae of growing puppies. It results from abnormal endochondral ossification, leading to cartilage thickening and potential vertebral deformities.
What is VOV in dogs? - in detail
VOV, or Von Willebrand Factor Deficiency, is an inherited bleeding disorder that affects dogs, much like hemophilia does in humans. This condition is caused by a deficiency or malfunction of von Willebrand factor (vWF), a protein crucial for blood clotting.
Dogs with VOV have impaired platelet function, leading to prolonged bleeding times after surgery, injury, or even minor procedures like tooth extraction. The disease is inherited through an autosomal recessive pattern, meaning both parents must carry the defective gene for their offspring to be affected.
Symptoms of VOV in dogs can vary widely and may include excessive bleeding during surgery or after injury, prolonged menstrual cycles in female dogs, and spontaneous nosebleeds or bruising. However, some dogs with VOV may show no signs at all until they experience a significant trauma or undergo a surgical procedure.
Diagnosing VOV typically involves blood tests that measure the levels and functionality of vWF in the dog's system. Treatment options are limited but can include administering desmopressin (DDAVP) to stimulate the release of stored vWF, or using factor VIII concentrates derived from human plasma. In severe cases, a splenectomy (removal of the spleen) may be recommended, as the spleen is a significant storage site for vWF.
Genetic testing can also help identify carriers and at-risk breeds, allowing for informed breeding practices to prevent the spread of this condition. Overall, understanding VOV in dogs is essential for veterinarians and dog owners alike to ensure proper care and management of affected animals.